Immunization Against Superficial Fungous Infection

Immunization of Lambs against infection with Echinucoccus granulsus using protoscolices and hydatid fluid antigens

Fungi and Fungous Diseases

variety of current theories (and it would seem, "facts"), this is a hard book to recommend to the student because of the wide variety of levels it presents. Demerec's extremely clear paper on genetic studies in bacteria starts off with an explanation of Mendelian factors and could easily illuminate a class of undergraduates, where Hogness' more sophisticated discussion of isolated viral DNA wou...

DNA immunization against experimental genital herpes simplex virus infection.

A nucleic acid vaccine, expressing the gene encoding herpes simplex virus (HSV) type 2 glycoprotein D (gD2) under control of the cytomegalovirus immediate-early gene promoter, was used to immunize guinea pigs against genital HSV-2 infection. The vaccine elicited humoral immune responses comparable to those seen after HSV-2 infection. Immunized animals exhibited protection from primary genital H...

Protection against Respiratory Syncytial Virus Infection by DNA Immunization

Respiratory syncytial virus (RSV) remains a major cause of morbidity and mortality in infants and the elderly and is a continuing challenge for vaccine development. A murine T helper cell (Th) type 2 response associates with enhanced lung pathology, which has been observed in past infant trials using formalin-inactivated RSV vaccine. In this study, we have engineered an optimized plasmid DNA ve...

Immunization against natural Helicobacter pylori infection in nonhuman primates.

Helicobacter pylori infection is widespread in some breeding groups of a rhesus monkey colony (71% H. pylori positive by 1 year), and the rate of seroconversion is also high. As a result, these groups can be used to test the safety and efficacy of an anti-H. pylori vaccine. Nine-month-old female animals were randomized to receive either 8 mg of recombinant urease (rUre) plus 25 microg of Escher...